Presented in this report are the methodological considerations for analyzing both existing data from a number of sources and new data to be collected by the PROMIS.
#Ifactor infographic pro
1,2 PRO measures include instruments that measure domains like health-related quality of life (HRQOL) and satisfaction with medical care. The Patient-Reported Outcomes Measurement Information System (PROMIS) project provides a unique opportunity to use advanced psychometric methods to construct, analyze and refine item banks, from which improved patient-reported outcome (PRO) instruments can be developed. Summarized are key analytic issues recommendations are provided for future evaluations of item banks in HRQOL assessment.
Analyses:Īnalyses include evaluation of data quality (eg, logic and range checking, spread of response distribution within an item), descriptive statistics (eg, frequencies, means), item response theory model assumptions (unidimensionality, local independence, monotonicity), model fit, differential item functioning, and item calibration for banking. This report provides an overview of the methods used in the PROMIS item analyses and proposed calibration of item banks. The PROMIS Steering Committee selected 5 HRQOL domains for initial focus: physical functioning, fatigue, pain, emotional distress, and social role participation. Item banks will be used as the foundation for developing short-form instruments and enabling computerized adaptive testing. The construction and evaluation of item banks to measure unidimensional constructs of health-related quality of life (HRQOL) is a fundamental objective of the Patient-Reported Outcomes Measurement Information System (PROMIS) project. Reeve, PhD, Outcomes Research Branch, National Cancer Institute, NIH, EPN 4005, 6130 Executive Blvd. Preparation of this work by non-NIH employees was supported by the National Institutes of Health through the NIH Roadmap for Medical Research Grant (AG015815), PROMIS Project. From the *National Cancer Institute, NIH, Bethesda, Maryland †UCLA Division of General Internal Medicine & Health Services Research, Los Angeles, California ‡QualityMetric Inc., Lincoln, Rhode Island, and the Health Assessment Lab, Waltham, Massachusetts §University of Washington, Seattle ♬olumbia University Stroud Center and Faculty of Medicine New York State Psychiatric Institute, and Research Division, Hebrew Home for the Aged in Riverdale, New York, New York ∥Psychology Department, University of North Carolina at Chapel Hill **Center for Health Outcomes Research, United BioSource Corporation, Bethesda, Maryland ††Psychology Department, University of Minnesota, Minneapolis ‡‡Center for Educational Assessment, University of Massachusetts at Amherst and §§Northwestern University Feinberg School of Medicine and Evanston Northwestern Healthcare, Evanston, Illinois.
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